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The title compound, C17H27BrO5, DEB, is a derivative of artemisinin which is used in malaria therapy. The OR-group at C12 is cis to the CH3-group at C11 and axially oriented on ring D which has a chair conformation. The ...
Artemisinin quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity
Novel artemisinin–quinoline hybrid-dimers were synthesized from dihydroartemisinin and different aminoquinolines at elevated temperatures (90–110 °C). All compounds were obtained as the β-isomers and were tested against ...