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Multifunctional enzyme inhibition for neuroprotection: a focus on MAO, NOS, and AChE inhibitors
(Elsevier, 2015)
Neurodegenerative disorders are known to be multifactorial in nature and current research focus has moved from a ‘one-drug-one-target approach’ to that of drugs which are able to act at various relevant biological targets. ...
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
(Elsevier, 2010)
Based on recent reports that several (E)-8-styrylcaffeinyl analogues are potent reversible inhibitors of
monoamine oxidase B (MAO-B), a series of 8-benzyloxycaffeinyl analogues were synthesized and evaluated
as inhibitors ...
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
(Elsevier, 2010)
Based on recent reports that several (E)-8-styrylcaffeinyl analogues are potent reversible inhibitors of monoamine oxidase B (MAO-B), a series of 8-benzyloxycaffeinyl analogues were synthesized and evaluated as inhibitors ...
Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues
(Elsevier, 2010)
Dual action antidepressants have important therapeutic implications. Methylene blue (MB), a charged compound structurally related to tricyclic antidepressants, acts on both monoamine oxidase (MAO) and the nitric oxide ...