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8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)
Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
Defensive coping and subclinical vascular disease risk – associations with autonomic exhaustion in Africans and caucasians: the SABPA study
(Elsevier, 2012)
Objective
The defensive active coping response is a recognised cardiovascular risk factor in Africans, especially in men. It is uncertain whether autonomic dysfunction might be the underlying cause. We therefore investigated ...
Ethnicity-specific differences in L-arginine status in South African men
(Nature Publishing Group, 2012)
The aetiology for an increasing incidence of hypertensive cardiovascular disease amongst Africans in southern Africa is unclear. Hypertension may be induced by inadequate release of L-arginine-derived nitric oxide impairing ...
Association of waist circumference with perception of own health in urban African males and females: the Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study
(Taylor & Francis, 2012)
Background: Current waist circumference (WC) cut-points of the Joint Statement Consensus (JSC) (male ≥ 94 cm, female ≥ 80 cm) were compared with a recently proposed WC cut-point (RPWC) (male ≥ 90 cm, female ≥ 98 cm). In ...
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA study
(Wiley, 2014)
Background
Incident atherothrombotic disease is predicted by leukocyte telomere length, a marker of biological age, and hemostatic factor levels, indicating a hypercoagulable state. We hypothesized that shorter telomeres ...