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Recent advances in understanding hypertension development in sub-Saharan Africa
(Nature, 2017)
Consistent reports indicate that hypertension is a particularly common finding in black populations. Hypertension occurs at
younger ages and is often more severe in terms of blood pressure levels and organ damage than in ...
Prevalence of hypertension in older people in Africa: a systematic review and meta-analysis
(Wolters Kluwer, 2017)
Objective: The prevalence of hypertension in older people living on the African continent has not been comprehensively assessed. We aimed to provide accurate estimates of hypertension prevalence and variations by major ...
Depression symptoms facilitated fibrinolytic dysregulation and future coronary artery disease risk in a black male cohort: the sympathetic activity and ambulatory blood pressure in Africans study
(Wolters Kluwer, 2017)
Background: Hypercoagulation is associated with coronary artery disease (CAD). Whether depression symptoms dysregulate inflammatory and hemostatic markers in an African cohort is not known; therefore, we assessed the ...
Change in renin, cardiovascular and inflammatory markers over three years in a black and white population: the SABPA study
(BioMed Central, 2017)
Background: To investigate if percentage change (%Δ) in renin over a 3 year follow-up is associated with %Δ in
cardiovascular and inflammatory markers in a low renin bi-ethnic group.
Methods: Blood pressure, active renin, ...
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: the SABPA study
(Elsevier, 2017)
Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the ...
Patient-related beliefs and adherence toward their medications among the adult hypertensive outpatients in Tanzania
(Future Medicine, 2017)
Aim: Hypertension is a leading global health problem requiring lifelong treatment. However, adherence to antihypertensive medicines is a problem, greater among developing countries. Consequently, there is a need to determine ...
Associations between dietary salt, potassium and blood pressure in South African adults: WHO SAGE Wave 2 Salt & Tobacco
(Elsevier, 2017)
Background & aims
In June 2016, South Africa implemented legislation mandating maximum sodium levels in a range of processed foods with a goal of reducing population salt intake and disease burden from hypertension. Our ...
Cardiac troponin T as early marker of subclinical cardiovascular deterioration in black hypertensive women
(Elsevier, 2017)
Background
Hypertensive heart disease is a rising concern, especially among black South African women. As high sensitivity cardiac troponin T (cTnT) is a marker of cardiomyocyte damage, we determined the potential link ...
The South African salt story: where are we and where are we heading?
(Karger, 2017)
Background and objectives:
The mortality and morbidity
burden caused by hypertension are preventable and therefore, efforts need to be taken to address this burden. Excess dietary sodium ...
May Measurement Month: a new joint global initiative by the International Society of Hypertension and the World Hypertension League to raise awareness of raised blood pressure
(Wolters Kluwer, 2017)
Raised blood pressure is the biggest single contributing risk factor to death and the burden of disease worldwide. However, international data suggest that fewer than half of those with hypertension are aware of their ...