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Comparative assessment of absolute cardiovascular disease risk characterization from non-laboratory-based risk assessment in South African populations
(BioMed Central, 2013)
Background: All rigorous primary cardiovascular disease (CVD) prevention guidelines recommend absolute CVD risk scores to identify high- and low-risk patients, but laboratory testing can be impractical in low- and middle-income ...
May Measurement Month 2017: results of 39 national blood pressure screening programmes
(Oxford Univ Press, 2019)
Raised blood pressure is the biggest single risk factor responsible for mortality worldwide. Despite this, the majority of people with hypertension are unaware of having it, are untreated, or are on treatment but uncontrolled. ...
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)
Background
Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ...
Ethnic differences regarding arterial stiffness of 6‐8‐year-old black and white boys
(Wolters Kluwer, 2017)
Objectives: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different ...
Prevalence of hypertension in older people in Africa: a systematic review and meta-analysis
(Wolters Kluwer, 2017)
Objective: The prevalence of hypertension in older people living on the African continent has not been comprehensively assessed. We aimed to provide accurate estimates of hypertension prevalence and variations by major ...
Leptin links with plasminogen activator inhibitor-1 in human obesity: the SABPA study
(Nature Publishing Group, 2015)
The relationship between obesity and the development of cardiovascular disease is well established. However, the underlying mechanisms contributing to vascular disease and increased cardiovascular risk in the obese remain ...
Soluble urokinase plasminogen activator receptor and hypertension among black South Africans after 5 years
(Nature Publishing Group, 2015)
Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker that links inflammation with cardiovascular risk. "However, studies linking suPAR and hypertension are scant. First, we determined whether baseline ...
Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
(Thieme, 2018)
An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ...
Ethnic-specific relationships between haemostatic and oxidative stress markers in black and white South Africans: the SABPA study
(Taylor & Francis, 2015)
Haemostatic– and oxidative stress markers are associated with increased cardiovascular risk. In the black population, evidence exists that both an imbalance in the haemostatic system and oxidative stress link with the ...
Retinal vessel calibres and haemostasis in black and white South Africans: the SABPA study
(Lippincott Williams & Wilkins, 2015)
Objectives: Retinal arteriolar narrowing associates with hypertension development and indicates increased cardiovascular risk. Evidence on whether the retinal vessel "calibres are related to the haemostatic system is ...