Search
Now showing items 31-40 of 49
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: the SABPA study
(Elsevier, 2017)
Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the ...
Longitudinal changes of cardiac troponin and inflammation reflect progressive myocyte stretch and likelihood for hypertension in a Black male cohort: the SABPA study
(Springer, 2019)
Inflammation was cross-sectionally associated with subclinical wall remodeling and hypertension. Whether longitudinal changes (∆) in inflammation, myocyte injury (troponin T), and stretch (N-terminal-pro-B-type natriuretic ...
Patient-related beliefs and adherence toward their medications among the adult hypertensive outpatients in Tanzania
(Future Medicine, 2017)
Aim: Hypertension is a leading global health problem requiring lifelong treatment. However, adherence to antihypertensive medicines is a problem, greater among developing countries. Consequently, there is a need to determine ...
Optimizing observer performance of clinic blood pressure measurement: a position statement from the Lancet Commission on Hypertension Group
(Wolters Kluwer, 2019)
High blood pressure (BP) is a highly prevalent modifiable cause of cardiovascular disease, stroke, and death. Accurate BP measurement is critical, given that a 5-mmHg measurement error may lead to incorrect hypertension ...
Associations between dietary salt, potassium and blood pressure in South African adults: WHO SAGE Wave 2 Salt & Tobacco
(Elsevier, 2017)
Background & aims
In June 2016, South Africa implemented legislation mandating maximum sodium levels in a range of processed foods with a goal of reducing population salt intake and disease burden from hypertension. Our ...
A comparison of the cardiometabolic profile of black South Africans with suspected non-alcoholic fatty liver disease (NAFLD) and excessive alcohol use
(Elsevier, 2015)
Excessive alcohol use and non–alcoholic fatty liver disease (NAFLD) are putative cardiovascular disease risk factors. In order to ease the identification of these conditions on primary health care level, we aimed to determine ...
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study
(Springer, 2016)
Nitric oxide (NO) synthesis capacity is determined by the availability of substrate(s) such as l-arginine and the influence of nitric oxide synthase (NOS) inhibitors, asymmetric dimethylarginine (ADMA) and symmetric ...
Cardiac troponin T as early marker of subclinical cardiovascular deterioration in black hypertensive women
(Elsevier, 2017)
Background
Hypertensive heart disease is a rising concern, especially among black South African women. As high sensitivity cardiac troponin T (cTnT) is a marker of cardiomyocyte damage, we determined the potential link ...
The South African salt story: where are we and where are we heading?
(Karger, 2017)
Background and objectives:
The mortality and morbidity
burden caused by hypertension are preventable and therefore, efforts need to be taken to address this burden. Excess dietary sodium ...
Leptin relates to prolonged cardiovascular recovery after acute stress in Africans: the SABPA study
(Elsevier, 2016)
Background and aims
Heightened cardiovascular reactivity and delayed recovery to stress are associated with an increased risk of cardiovascular disease. Africans, who are more prone to develop hypertension, show greater ...