Now showing items 41-44 of 44
Synthesis and antimycobacterial activity of disubstituted benzyltriazoles
The increasing prevalence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb), the pathogen of human tuberculosis (TB), serves as a strong incentive for the discovery and development of new agents for the ...
Single-step synthesis and in vitro anti-mycobacterial activity of novel nitrofurantoin analogues
The emergence of drug-resistant tuberculosis (DR-TB) as well as the requirement for long, expensive and toxic drug regimens impede efforts to control and eliminate TB. Therefore, there’s a need for effective and affordable ...
Synthesis and in vitro antimycobacterial and antileishmanial activities of hydroquinone-triazole hybrids
Infectious diseases such as tuberculosis and leishmaniasis are leading causes of human death. One of the major factors contributing to the poor control of these diseases is primarily the reduced effectiveness of the existing ...
Inhibitory effects of novel ciprofloxacin derivatives on the growth of four Babesia species and Theileria equi
The problems of parasite resistance, as well as the toxic residues to most of the commercially available antipiroplasmic drugs severely weaken their effective, curative, and environmental safe employment. Therefore, it is ...