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Testosterone and acute stress are associated with fibrinogen and Von Willebrand factor in African men: the SABPA study
(Elsevier, 2013)
Background: Low testosterone, acute and chronic stress and hypercoagulation are all associated with hypertension
and hypertension-related diseases. The interaction between these factors and future risk for coronary ...
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)
Background
Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ...
Ethnic differences regarding arterial stiffness of 6‐8‐year-old black and white boys
(Wolters Kluwer, 2017)
Objectives: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different ...
Thiobarbituric acid-reactive substances relate to arterial stiffness and blood pressure in 6 to 8-year-old boys stratified by maternal risk
(Nature, 2018)
Early cardiovascular disease (CVD) onset can be inflicted by familial cardiovascular and lifestyle risk factors. We aimed to compare phenotypic characteristics and explore associations between oxidative stress and vascular ...
Cornell product relates to albuminuria in hypertensive black adults independently of blood pressure: the SABPA study
(Elsevier, 2015)
Evidence of the relationship between left ventricular hypertrophy and urinary albumin excretion is contradictory and limited in black adults in whom hypertensive heart disease is common. We aimed to investigate the ...
GC-MS quantification of urinary symmetric dimethylarginine (SDMA), a whole-body symmetric l-arginine methylation index
(Elsevier, 2018)
Circulating and excretory NG,N´G-dimethyl-l-arginine (symmetric dimethylarginine, SDMA) and NG,NG-dimethyl-l-arginine (asymmetric dimethylarginine, ADMA) are cardiovascular risk factors. Despite close chemical structures, ...
Left ventricular mass independently associates with 24-hour sodium excretion in young masked hypertensive adults: the African-PREDICT study
(Elsevier, 2019)
Background
Due to the known contribution of excess sodium intake on elevations in blood pressure, salt reduction regulations are being introduced in countries all over the world. To study the contribution of sodium intake ...
The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study
(Springer Nature, 2017)
Both endothelin-1 and oxidative stress have important roles in the development of cardiovascular diseases such as hypertension and atherosclerosis. Limited information is available on the interaction between oxidative ...
Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study
(Nature, 2020)
Hypertension is common in black populations and is known to be associated with low nitric oxide (NO) bioavailability. We compared plasma and urinary NO-related markers and plasma creatine kinase (CK) levels between young ...
Phenotypic predictors of aortic root dilation in essential hypertension
(Sage, 2020)
Several life-threatening complications can develop in
the ascending aorta, which include dissection or rupture of an aortic aneurysm. Those at high risk of developing such complications can be categorised according
to ...