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Adipokines and cardiometabolic function: how are they interlinked?
Objective Adipokines contribute directly to the coexistence of insulin resistance and endothelial dysfunction. Most studies focus on a single adipokine. We therefore investigated the independent relationships of leptin, ...
A significant decline in IGF-I may predispose young Africans to subsequent cardiometabolic vulnerability
(Oxford Univ Press, 2010)
Objectives: Low serum IGF-I is an independent risk factor for diabetes and cardiovascular disease. These noncommunicable diseases are extremely common in urban black South Africans, but their IGF-I concentration is unknown. ...
Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians
Objective Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations, asymmetric ...
Serum calcium revisited: associations with 24-h ambulatory blood pressure and cardiovascular reactivity in Africans
Sub-Saharan Africans face an increasing burden of hypertension. Although controversial, recent experimental evidence strongly suggests that serum calcium contributes to elevated blood pressure through increased vascular ...