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Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides
(Elsevier, 2014)
A series of 4-aminoquinolinyl-chalcone amides 11–19 were synthesized through condensation of carboxylic
acid-functionalized chalcone with aminoquinolines, using 1,10-carbonyldiimidazole as coupling
agent. These compounds ...
Recent progress in the development of anti-malarial quinolones
(BioMed Central, 2014)
Available anti-malarial tools have over the ten-year period prior to 2012 dramatically reduced the number of fatalities
due to malaria from one million to less than six-hundred and thirty thousand. Although fewer people ...
Synthesis and in vitro biological evaluation of aminoacridines and artemisinin-acridine hybrids
(Elsevier, 2014)
During this study, 9-aminoacridine and artemisinin–acridine hybrid compounds were synthesized and the in vitro for antimalarial activity against both the chloroquine sensitive but also gametocytocidal strain (NF54), and ...