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Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents
(Elsevier, 2014)
The aim of this study was to design drug-like molecules with multiple neuroprotective mechanisms
which would ultimately inhibit N-methyl-D-aspartate (NMDA) receptors, block L-type voltage gated
calcium channels (VGCC) ...
In vitro evaluation of the cytotoxic and apoptogenic properties of aloe whole leaf and gel materials
(Taylor & Francis, 2014)
Aloe gel and whole-leaf materials have shown biological effects with potential therapeutic
applications, and recently, their drug-absorption enhancement properties have been discovered.
It is important to establish a ...
Synthesis and in vitro biological evaluation of aminoacridines and artemisinin-acridine hybrids
(Elsevier, 2014)
During this study, 9-aminoacridine and artemisinin–acridine hybrid compounds were synthesized and the in vitro for antimalarial activity against both the chloroquine sensitive but also gametocytocidal strain (NF54), and ...