Now showing items 1-6 of 6
Efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for bipolar depression: study protocol for a proof-of-concept trial
(ABP - Brazilian Psychiatric Association, 2019)
Objective: Bipolar depression is characterized by neurobiological features including perturbed oxidative biology, reduction in antioxidant levels, and a concomitant rise in oxidative stress markers. Bipolar depression ...
Prevalence of comorbidities in women with and without breast cancer in Soweto, South Africa: results from the SABC study
Background. Comorbidities occurring concurrently in breast cancer patients can be burdensome, as they may negatively influence time and stage of presentation. Objectives. To describe the comorbid health conditions among ...
High sedentary behaviour and low physical activity are associated with anxiety and depression in Myanmar and Vietnam
The study aimed to estimate independent and combined associations of sedentary behaviour and physical activity with anxiety and depression among chronic disease patients in Myanmar and Vietnam. The cross-sectional sample ...
Animal models of major depressive disorder and the implications for drug discovery and development
(Taylor & Francis, 2019)
Introduction: Depression is a highly debilitating psychiatric disorder that affects the global population and causes severe disabilities and suicide. Depression pathogenesis remains poorly understood, and the disorder is ...
High sedentary behavior is associated with depression among rural South Africans
The study aimed to investigate the association between sedentary behavior and depression among rural South Africans. Data were analyzed from the cross-sectional baseline survey of the “Health and Aging in Africa: A ...
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression
(Cambridge Univ Press, 2019)
Objectives: Treatment-resistance to antidepressants is a major problem in the pharmacotherapy of major depressive disorder (MDD). Unfortunately, only a few animal models are suitable for studying treatment-resistant ...