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Selectively bred rodents as models of depression and anxiety
Stress related diseases such as depression and anxiety have a high degree of co morbidity, and represent one of the greatest therapeutic challenges for the twenty-first century. The present chapter will summarize existing ...
Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide S receptor activity
(Society for Neuroscience, 2015)
Neuropeptide S (NPS) has generated substantial interest due to its anxiolytic and fear-attenuating effects in rodents, while a corresponding receptor polymorphism associated with increased NPS receptor (NPSR1) surface ...