Now showing items 1-2 of 2
Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression
Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested ...
Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression
(Cambridge Univ Press, 2015)
Objective: We investigated whether the nitric oxide (NO) precursor, L-arginine, can prevent the antidepressant-like action of the fast-acting antidepressant, ketamine, in a genetic rat model of depression, and/or induce ...