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Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression
Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested ...
Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli
Depression is a debilitating mental illness and two thirds of patients respond insufficiently to conventional antidepressants. Electroconvulsive therapy (ECT) remains the most effective treatment to alleviate drug-refractory ...