Browsing Faculty of Natural and Agricultural Sciences by Author "Taylor, Geoffrey A."
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Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing
Greaves, Laura, C.; Elson, Joanna L.; Nooteboom, Marco; Tuppen, Helen A.L.; Taylor, Geoffrey A. (PLoS, 2014)Age-related decline in the integrity of mitochondria is an important contributor to the human ageing process. In a number of ageing stem cell populations, this decline in mitochondrial function is due to clonal expansion ...