Browsing Faculty of Natural and Agricultural Sciences by Subject "Lactacystin"
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Pedunculopontine cell loss and protein aggregation direct microglia activation in parkinsonian rats
(Springer, 2016)We previously reported a loss of cholinergic neurons within the pedunculopontine tegmental nucleus (PPTg) in rats that had been intra-nigrally lesioned with the proteasomal inhibitor lactacystin, with levels of neuronal ... -
Temporal-spatial profiling of pedunculopontine galanin-cholinergic neurons in the lactacystin rat model of Parkinson’s disease
(Springer, 2017)Parkinson’s disease (PD) is conventionally seen as resulting from single-system neurodegeneration affecting nigrostriatal dopaminergic neurons. However, accumulating evidence indicates multi-system degeneration and ...