Browsing Faculty of Natural and Agricultural Sciences by Subject "Phenotyping"

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    • Metallothionein 1 overexpression does not protect against mitochondrial disease pathology in Ndufs4 knockout mice 

      Miller, Hayley Christy; Louw, Roan; Mereis, Michelle; Venter, Gerda; Boshoff, John-Drew; Mienie, Liesel; Van Reenen, Mari; Venter, Marianne; Lindeque, Jeremie Zander; Van der Westhuizen, Francois Hendrikus (Springer, 2021)
      Mitochondrial diseases (MD), such as Leigh syndrome (LS), present with severe neurological and muscular phenotypes in patients, but have no known cure and limited treatment options. Based on their neuroprotective effects ...