Browsing Faculty of Natural and Agricultural Sciences by Subject "Solubility"
Now showing items 1-3 of 3
-
All-atomistic molecular dynamics (AA-MD) studies and pharmacokinetic performance of PAMAM-dendrimer-furosemide delivery systems
(Elsevier, 2018)Improvement of problematic dissolution and solubility properties of a model drug, furosemide, was investigated for poly(amidoamine) (PAMAM) dendrimer complexes of the drug. Full and half generation dendrimers with amino ... -
Experimental and mesoscale computational dynamics studies of therelationship between solubility and release of quercetin from PEG solid dispersions
(Elsevier, 2013)The flavonol quercetin is potentially clinically relevant for its antimicrobial, beneficial cardiovasculareffects, cancer treatment amongst others. However, its successful therapeutic application is severelycurtailed by ... -
Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity
(Elsevier, 2013)Silver sulfadiazine (AgSD) is a topical antibiotic with limited aqueous solubility. In this study, it was shown that poly(amido amine) (PAMAM) dendrimer complexes with SD (SDZ) and silver (Ag) could be used for a bottom-up ...