Browsing Faculty of Natural and Agricultural Sciences by Subject "Metabolomics"
Now showing items 1-10 of 56
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Abalone growth and associated aspects: now from a metabolic perspective
(Wiley, 2018)Worldwide, there are approximately 100 Haliotis species, more commonly known as abalone or ‘Paua’ in New Zealand, ‘Venus's‐ears’ in Greece, ‘Awabi’ in Japan, ‘Perlemoen’ in South Africa and ‘Ormers’ in Europe. Regardless ... -
The altered human serum metabolome induced by a marathon
(Springer, 2018)Introduction Endurance races have been associated with a substantial amount of adverse effects which could lead to chronic disease and long-term performance impairment. However, little is known about the holistic metabolic ... -
The application of metabolomics toward pulmonary tuberculosis research
(Elsevier, 2019)In the quest to identify novel biomarkers for pulmonary tuberculosis (TB), high-throughput systems biology approaches such as metabolomics has become increasingly widespread. Such biomarkers have not only successfully been ... -
Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test
(Nature, 2019)The mitochondrial energy score (MES) protocol, developed by the Myhill group, is marketed as a diagnostic test for chronic fatigue syndrome/Myalgic Encephalomyelitis (CFS/ME). This study assessed the reliability and ... -
Can a metabolomics-based approach be used as alternative to analyse fatty acid methyl esters from soil microbial communities?
(Elsevier, 2016)Modern high-throughput approaches such as metabolomics, holds promise for investigating microbial communities. This study evaluated the quantitative and qualitative data generation potential of a metabolomics-based approach ... -
Central systolic pressure and a nonessential amino acid metabolomics profile: the African prospective study on the early detection and identification of cardiovascular disease and hypertension
(Wolters Kluwer, 2019)Objectives: Early-life exposures to cardiovascular risk factors may manifest as early vascular ageing, a phenomenon to which black populations are more prone. The metabolome provides insight into the current state and ... -
Characterising the metabolic differences related to growth variation in farmed Haliotis midae
(Elsevier, 2018)The South African abalone farming industry is entirely based on Haliotis midae, which has been commercially cultured with great success the last 20 years. Even though abalone are cultivated under identical farming conditions, ... -
A comparison of four sputum pre-extraction preparation methods for identifying and characterising Mycobacterium tuberculosis using GCxGC-TOFMS metabolomics
(Elsevier, 2012)In many pulmonary diseases, sputum is a valuable sample material for use in disease characterisation and diagnostics. However, due to its high viscosity and uneven consistency (lumpiness), it is difficult to obtain ... -
A comparison of two extraction methods for differentiating and characterising various Mycobacterium species and Pseudomonas aeruginosa using GC-MS metabolomics
(Academic Journals, 2012)We investigated the capacity of a metabolomics research approach to characterise and differentiate between various infectious Mycobacterium species and Pseudomonas aeruginosa, and compared two extraction procedures; 1) ... -
Concurrent class analysis identifies discriminatory variables from metabolomics data on isovaleric acidemia
(Springer, 2012)Metabolomics data are typically complex and high dimensional. Multivariate dimension-reducing techniques have thus been developed for analysing metabolomics data to disclose underlying relationships, with principal component ...