Browsing Electronic Theses and Dissertations (ETDs) by Subject "Artemisinin"
Now showing items 1-5 of 5
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Artemisinin–quinoline hybrids : design, synthesis and antimalarial activity
(North-West University, 2013)Introduction - Malaria is a major global health problem, with more than 500 million reported cases and at least 1 million deaths each year. The main problem with malaria control is the emerging drug resistance. Plasmodium ... -
Investigating the absorptive and secretory transport of selected anti-malarial drugs
(North-West University, 2018)Malaria is one of the predominant infectious diseases affecting more than 200 million people a year worldwide. Artemisinin combination therapy (ACT) is currently the frontline treatment against the Plasmodium falciparum ... -
Synthesis and antimalarial activity screening of artemisinin-acridine hybrids
(2013)Malaria endemic areas not only pose a public health threat, but affects 3.3 billion people worldwide. In 2011, estimated malaria related deaths amounted to 660 000 out of 219 million reported cases, with 81% of these and ... -
Synthesis and biological evaluation of novel artemisone derivatives
(North-West University (South Africa) , Potchefstroom Campus, 2015)Despite intensive international efforts to eradicate malaria, the disease, continues to inflict an enormous toll on human lives, especially in Africa. An estimated 198 million malaria cases and 584, 000 deaths were reported ... -
Synthesis, cytotoxicity and antiplasmodial activity of novel ferrocenyl-artemisinin hybrids
(North-West University (South-Africa). Potchefstroom Campus, 2019)Malaria is caused by a parasite of the genus Plasmodium. Of the five species that infect humans, Plasmodium falciparum is the most dangerous. This disease caused 435 thousand deaths in 2017. It is estimated that 266 thousand ...