Search
Now showing items 11-20 of 61
The effect of selected natural oils on the permeation of flurbiprofen through human skin
(North-West University, 2012)
In pharmaceutical sciences, topical delivery is a transport process of an active pharmaceutical ingredient (API) from a formulated dosage form to the target site of action. For most topical delivery systems, the skin ...
Formulation and topical delivery of lidocaine and prilocaine with the use of Pheroid™ technology
(North-West University, 2012)
Local anaesthetics are used regularly in the medical world for a variety of different procedures. Topical anaesthetics are used largely in minor skin breaking procedures, laceration repair and minor surgical procedures ...
The implementation of the delivery gap principle to develop an effective transdermal delivery system for caffeine
(2013)
Caffeine is frequently used in cosmetics due to its well-characterised skin permeation properties and is widely incorporated in cosmetic-related products intended for skin (Samah & Heard, 2013:631). Despite its polar ...
Formulation, in vitro release and transdermal diffusion of pravastatin by the implementation of the delivery gap principle
(2014)
Active pharmaceutical ingredients (APIs), which are incorporated in different formulations, i.e. creams, gels, foams, etc., are applied to the skin for a therapeutic effect. This therapeutic effect could either be required ...
The influence of pH on the in vitro skin permeation of rhodium
(2014)
In occupational settings where rhodium is produced or used, such as the mining industry, refineries and catalytic industries, workers are at risk of being dermally exposed to this metal in either the metallic form or its ...
In vitro skin permeation of selected platinum group metals
(2014)
Background: Platinum group metal (PGM) mining and refining is a large constituent of the mining sector of South Africa and contributes significantly to the gross domestic product. The PGMs include the rare metals platinum ...
A comparative study between two lamellar gel phase systems and Emzaloids as delivery vehicles for the transdermal delivery of 5-fluorouracil and idoxuridine
(North-West University, 2004)
The distinctive architecture of the stratum corneum with its unique nature of an
interstitial lipoidal environment plays the major role in regulating the barrier function of the skin. The major problem with the transdermal ...
Formulation, in vitro release and transdermal diffusion of selected retinoids
(North-West University, 2010)
Acne is a multifactorial skin disease affecting about 80 % of people aged 11 to 30. Several systemic and topical treatments are used to treat existing lesions, prevent scarring and suppress the development of new lesions. ...
The transdermal delivery of various anti–emetics
(North-West University, 2010)
Motion sickness, although viewed as a sickness, is in actuality a psychophysiological response to motion. The most common cause of motion sickness is the mismatch between the vestibular and visual systems. An increase in ...
Transdermal diffusion stability and clinical efficacy of cosmetic formulations containing Rosa rubiginosa rosehip seed oil
(North-West University (South Africa) , Potchefstroom Campus, 2016)
This study aimed at investigating cosmeceutical product development from concept to clinical efficacy testing, using Rosa rubiginosa rosehip seed oil, sourced from Southern African soil.
Rosehip seed oil contains various ...