Browsing Health Sciences by Subject "Enzyme inhibition"
Now showing items 1-3 of 3
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Discovery of catechol-O-methyltransferase inhibitors through virtual screening
(North-West University (South Africa) , Potchefstroom Campus, 2016)BACKGROUND AND RATIONALE: Parkinson’s disease (PD) is a progressive neurodegenerative disease that is caused by the death of dopaminergic neurons in the substantia nigra resulting in a loss of dopamine in the striatum. ... -
In vitro evaluation of the enzyme inhibition and membrane permeation properties of benzophenones extracted from honeybush
(North-West University (South Africa) , Potchefstroom Campus, 2016)Tea prepared from the honeybush (Cyclopia spp.) plant has become a popular beverage and has been shown to possess medicinal properties. Honeybush plants contain phytochemicals that can contribute to the prevention of certain ... -
Screening of virtual libraries for monoamine oxidase inhibitors
(2013)The traditional view of drug design is that a single drug should interact with a single molecular target. As science progressed, there was an understanding that most drugs interact with more than one target and that ...