Browsing Health Sciences by Subject "Extrusion-spheronisation"
Now showing items 1-6 of 6
-
Cassava starch as modified release excipient in selected gliclazide oral dosage forms
(North-West University (South Africa) , Potchefstroom Campus, 2015)Solid oral dosage forms are still the most leading delivery system employed commercially due to the ease in which it can be handled, administered and even transported. Several varieties of solid oral dosage forms are ... -
Development of a compressed bead-in-capsule drug delivery system for sustained release
(North-West University (South Africa) , Potchefstroom Campus, 2015)Multiple-unit pellet systems (MUPS) are solid oral dosage forms consisting of multi-particulates (e.g. coated and/or uncoated beads) compressed into mini-tablets or tablets; or they may be loaded into hard gelatine ... -
Development of a double phase dosage form for enhanced peptide drug delivery
(2015)Parenteral administration remains the most utilised route of administration for therapeutic peptides due to low intestinal epithelial permeability. However, the most convenient and popular route of drug administration ... -
Development of a multiple-unit sustained release dosage form containing gliclazide
(North-West University, 2018)Multiple-unit drug delivery systems (MUDS) are oral dosage forms consisting of beads or pellets (either coated or uncoated) that may be compressed into tablets or encapsulated. Tablets consisting of beads have been ... -
Development of multiple-unit pellet systems by employing the SeDeM expert diagram system
(North-West University (South Africa), 2018)Conventional tablets and capsules are considered the most common and acceptable drug delivery systems, however, in recent years multiple unit pellet systems (MUPS) have become more popular and are considered to be an ... -
Preparation and evaluation of multiple-unit solid oral dosage forms containing chemical permeation enhancing agents
(2014)The most popular and convenient route of drug administration remains the oral route, however, protein and peptide drugs such as insulin have poor membrane permeability and stability in the gastrointestinal tract. Absorption ...