Browsing Health Sciences by Subject "Fluoxetine"
Now showing items 1-6 of 6
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Chronic effects of pre-adolescent pharmacological and non-pharmacological interventions on depressive-like behaviour in rats
(North-West University, 2018)Similar to adults, major depressive disorder (MDD) also affects children and adolescents, with comparable treatment outcomes. However, only two antidepressants, namely the serotonin reuptake inhibitors fluoxetine and ... -
Early-life exposure to fluoxetine and/or exercise on bio-behavioural markers of depression in early adulthood in stress sensitive rats
(North-West University (South Africa) , Potchefstroom Campus, 2015)Juvenile depression is a major concern worldwide, with only the selective serotonin reuptake inhibitors (SSRIs) fluoxetine and escitalopram approved for treatment. The effects of early-life exposure to SSRIs on neurodevelopment ... -
The involvement of nitric oxide in a rodent model of post-traumatic stress disorder
(North-West University, 2003)Post-traumatic stress disorder (PTSD), an anxiety disorder, may develop after experiencing or witnessing a severe traumatic event. Characteristic symptoms include hyper arousal and amnesic symptoms, while volume reductions ... -
The long-term effects of fluoxetine on stress-related behaviour and acute monoaminergic stress response in stress sensitive rats
(2014)Fluoxetine and escitalopram are the only antidepressants approved by the Food and Drug Administration of the United States of America (FDA) for treatment of major depression in children and adolescents. Both drugs are ... -
The modulating effect of myo-inositol and other antidepressants on the mRNA levels and protein expression of selected subcellular enzymes
(North-West University, 2005)Myo-lnositol (mIns), a natural component of the human diet and essential precursor of several signalling pathways, including that of G protein-coupled receptors, has also been shown to be effective in the treatment of ... -
The role of myo-inositol in G-protein coupled receptor-mediated sub-cellular transduction mechanisms in neuronal cell lines
(North-West University, 2003)myo-lnositol (ml), a simple polyol isomer of glucose, is an important osmolyte in the brain and a precursor of the phosphatidyl inositol metabolic pathway. It is known to facilitate various cellular events such as membrane ...