Browsing Health Sciences by Subject "Selectivity"
Now showing items 1-3 of 3
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Monoamine oxidase inhibition by novel quinolinones
(2014)Parkinson’s disease (PD) is an age-related neurodegenerative disorder. The degeneration of the neurons of the substantia nigra in the midbrain leads to the loss of dopamine from the striatum, which is responsible for the ... -
Synthesis and evaluation of 1-indanone derivatives as inhibitors of monoamine oxidase
(North-West University (South Africa) , Potchefstroom Campus, 2016)Parkinson‘s disease (PD) is a neurodegenerative disorder characterised by the death of neurons in the substantia nigra pars compacta (SNpc) in the midbrain leading to a dopamine (DA) deficiency. This deficiency is responsible ... -
Synthesis and evaluation of 3,4-Dihydro-3-methyl-2(1H)-quinazolinone derivatives as monoamine oxidase inhibitors
(North-West University, Potchefstroom Campus, 2018)Parkinson’s disease (PD) is an age related neurodegenerative disorder. Loss of dopamine from the striatum is responsible for the motor symptoms of PD. This loss of dopamine is due to degeneration of the neurons of the ...