Browsing Health Sciences by Subject "Antidepressant"
Now showing items 1-4 of 4
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The antidepressant properties of selected methylene blue analogues
(2014)The shortcomings of current antidepressant agents prompts the design of novel multimodal antidepressants and the identification of new antidepressant targets, especially those located at sub-cellular level. Such ... -
Characterisation of the ?2A-adrenoceptor antagonism by mirtazapine and its modifying effects on receptor signalling
(North-West University, 2004)Mirtazapine is an atypical antidepressant employed clinically for the treatment of major depression. As a multipotent antagonist it acts at α2a-adrenergic receptors (α2a -ARs). serotonin type-2A receptors (5-HT2a-Rs) and ... -
Prescribing patterns of antidepressants with known off–label indications among adults
(2014)“Off-label use” is defined as the use of medicine for indications other than recommended or registered for, e.g. the prescribing of a particular active substance for a patient younger than the substance is recommended or ... -
The role of the NO-cGMP pathway as a putative target in antidepressant action
(North-West University, 2004)Depressive disorders are among the most frequent psychiatric diseases in the Western world with prevalence between 9% and 18%. Poor compliance and inappropriate antidepressant discontinuation invokes long-term morbidity, ...