Browsing Health Sciences by Subject "Quinazolinone"
Now showing items 1-2 of 2
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Adenosine A1/A2A receptor antagonistic properties of selected 2-substituted benzoxazinone and quinazolinone derivatives
(North-West University (South Africa), Potchefstroom Campus, 2018)The A1 and A2A adenosine receptor antagonists are the subject of extensive research based on their aptitude for ameliorating Parkinson’s disease related cognitive deficits (A1 adenosine receptor subtype) and motor dysfunction ... -
Design, synthesis and evaluation of quinazolinone analogues as monoamine oxidase inhibitors
(North-West University (South Africa), Potchefstroom Campus, 2018)Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease, and it is estimated to affect approximately 1% of the population over the age of 65. PD is characterised by non-motor ...