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Screening of virtual libraries for monoamine oxidase inhibitors
The traditional view of drug design is that a single drug should interact with a single molecular target. As science progressed, there was an understanding that most drugs interact with more than one target and that ...
Genetic and perinatal risk factors for movement disorders
(North-West University, Potchefstroom Campus., 2018)
Movement disorders, such as Parkinson's disease (PD), Huntington's disease (HD) and cerebral palsy (CP) are debilitating diseases with a great societal impact. These disorders are characterized by damage to the basal ...