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The implementation of the delivery gap principle to develop an effective transdermal delivery system for caffeine
(2013)
Caffeine is frequently used in cosmetics due to its well-characterised skin permeation properties and is widely incorporated in cosmetic-related products intended for skin (Samah & Heard, 2013:631). Despite its polar ...
The transdermal delivery of various anti–emetics
(North-West University, 2010)
Motion sickness, although viewed as a sickness, is in actuality a psychophysiological response to motion. The most common cause of motion sickness is the mismatch between the vestibular and visual systems. An increase in ...
Pheroid® technology in the transdermal delivery of selected non-steroidal anti-inflammatory drugs
(North-West University (South Africa) , Potchefstroom Campus, 2015)
Drug delivery through the skin still remains an area that enjoys active research with much of the research focusing on physical or chemical methods to reversibly alter the skin’s permeability to compounds because of the ...
Transdermal penetration enhancement and clinical efficacy of Aloe marlothii and Aloe ferox compared to Aloe vera
(2014)
Extensive research has already been performed on Aloe vera therefore it is important that researchers include other aloe species, such as Aloe marlothii and Aloe ferox, in studies involving aloe plant materials (Loots et ...
Characterisation, toxicology and clinical effects of crocodile oil in skin products
(North-West University, 2012)
Natural oils are regularly used in cosmetics and as treatment for numeral skin conditions (Nielsen, 2006:575). The natural products industry is a multibillion dollar industry and has grown tremendously over the past few ...
Formulation, in vitro release and transdermal diffusion of pravastatin by the implementation of the delivery gap principle
(2014)
Active pharmaceutical ingredients (APIs), which are incorporated in different formulations, i.e. creams, gels, foams, etc., are applied to the skin for a therapeutic effect. This therapeutic effect could either be required ...
Formulation and topical delivery of lidocaine and prilocaine with the use of Pheroid™ technology
(North-West University, 2012)
Local anaesthetics are used regularly in the medical world for a variety of different procedures. Topical anaesthetics are used largely in minor skin breaking procedures, laceration repair and minor surgical procedures ...
Pheroid technology for the topical delivery of depigmenting agents transforming growth factor–ß1 and tumor necrosis factor–a
(North-West University, 2010)
Pigmentation disorders occur in multiple conditions (Hakozaki et al., 2006:105). Although many modalities of treatments are available, none are completely satisfactory (Briganti et al., 2003:101). Two cytokines normally ...
The synthesis and transdermal delivery of stavudine derivatives
(North-West University, 2006)
The skin is an amazingly flexible and relatively impermeable barrier that provides
protective, perceptive and communication functions to the human body. The interest in
transdermal drug delivery may be attributed to the ...
PheroidTM technology for the topical application of selected cosmeceutical actives
(North-West University, 2008)
Aging can be described as an extremely complex occurrence from which no organism can be excluded. Intrinsic and extrinsic aging make out the two components of skin aging and they differ on the macromolecular level while ...