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The synthesis and transdermal delivery of stavudine derivatives
(North-West University, 2006)
The skin is an amazingly flexible and relatively impermeable barrier that provides
protective, perceptive and communication functions to the human body. The interest in
transdermal drug delivery may be attributed to the ...
PheroidTM technology for the topical application of selected cosmeceutical actives
(North-West University, 2008)
Aging can be described as an extremely complex occurrence from which no organism can be excluded. Intrinsic and extrinsic aging make out the two components of skin aging and they differ on the macromolecular level while ...
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)
The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ...
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)
Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ...
Pheroid technology for the topical delivery of insulin growth factor 1 (IGF-1), keratinocyte growth factor (KGF) and vascular endothelial growth factor (VEGF)
(North-West University, 2009)
The biotechnological era is here and many peptides and proteins are being used as part of
drug therapy. They are, however, not very stable and do not have the physicochemical
properties that allow for oral or topical ...