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In vitro investigation of wound dynamics using Absorbatox® containing organic acid(s)
(North-West University (South-Africa), 2020)
The skin provides an essential protective barrier between the internal tissues and the environment. A wound is defined as a defect or a break in the skin barrier as a result of physical or thermal damage. Wounds may also ...
Artesunate - An investigation into polymorphism
(North-West University (South-Africa), 2020)
Artesunate (ART) is a derivative of artemisinin and is used in the treatment of uncomplicated Plasmodium falciparum (P. falciparum) malaria. Limited and unreliable solid-state and physico-chemical data is currently available ...
Rifampicin raw materials complexities and approaches to address solubility and in vitro permeability
(North-West University (South-Africa), 2021)
Tuberculosis is classified as a global emergency because it is taking lives at an alarming rate and developing countries with insufficient health care systems are primarily affected. Fixed dose combination drugs (FDCs) ...
In vitro efficacy of cations incorporated in Absorbatox® for wound healing
(North-West University (South-Africa), 2020)
Wound healing can be described as a cascade of cells activated to restore tissue integrity, in order to regain the body’s natural function. Wound care plays a pivotal role in achieving therapeutic outcomes in wounds to ...
The development of paracetamol and dapsone amorphous solid dispersions
(North-West University (South-Africa), 2021)
The development of APIs was focused on the crystalline form over the years, but as the poor
solubility of new drugs increased, the focus turned to developing the amorphous form of the
drug. Dapsone (DAP) is no exception, ...