Background: Fibulin-1, an extracellular matrix component and mediator in cardiac fibrosis, is expressed in cardiac valves, heart muscles and blood vessels and may contribute to different cardiovascular pathological ...

Motivation - African populations are more prone to the development of left ventricular structure abnormalities and dysfunction, however limited information exists on potential metabolic pathways contributing to early left ...

Motivation - The accurate measurement of blood pressure remains the most essential technique for the diagnosis and management of hypertension. In addition, there is increasing evidence that the measurement of clinic blood ...

Background and motivation: Myeloperoxidase (MPO) is an enzyme with both pro-inflammatory and pro-oxidative functions. Previous studies in the United States have found MPO levels to be higher in African American than in ...

Background and motivation: The global burden of cardiovascular disease (CVD) including hypertension is ever-increasing, especially in the South African context. Nitric oxide (NO) plays a vital role in normal vascular ...