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Topical delivery of selected female hormones from different formulations
(North-West University (South-Africa), 2020)
Skin ageing is an unavoidable biological phenomenon inextricably linked to menopause. The rapid and drastic decline in oestrogen levels brought about by menopause has a profound effect on skin integrity and physiology, ...
The use of grapeseed oil emulsions for the transdermal delivery of selected statins
(North-West University (South-Africa), 2020)
Statins are used for the medical treatment of hypercholesterolemia, but after oral administration, it may cause gastro-intestinal disturbances and first-pass hepatic metabolism may decrease the bioavailability. Hence, the ...
Transdermal delivery of selected statins formulated in grapeseed oil emulsions
(North-West University (South-Africa), 2020)
Hypercholesterolemia can be described as high levels of low-density lipoproteins (LDL) that accumulate in the cells of the body including the liver, spleen and the intestines. Cholesterol is eliminated by increasing ...
In vitro investigation of wound dynamics using Absorbatox® containing organic acid(s)
(North-West University (South-Africa), 2020)
The skin provides an essential protective barrier between the internal tissues and the environment. A wound is defined as a defect or a break in the skin barrier as a result of physical or thermal damage. Wounds may also ...
In vitro efficacy of cations incorporated in Absorbatox® for wound healing
(North-West University (South-Africa), 2020)
Wound healing can be described as a cascade of cells activated to restore tissue integrity, in order to regain the body’s natural function. Wound care plays a pivotal role in achieving therapeutic outcomes in wounds to ...
Comparative study of the topical delivery of selected female hormones
(North-West University (South-Africa), 2020)
Intrinsic skin ageing is predominantly caused by a decrease in female hormones as menopause approaches. It is suggested that topical application of female hormones may treat these ageing symptoms. Unfortunately, the ...
Formulation of an emulgel for topical delivery of roxithromycin
(North-West University (South-Africa), 2020)
The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ...