Motivation - In sub-Saharan Africa, the burden of cardiovascular diseases (CVD) is increasing at an alarming rate. This may be due to the rapid urbanisation of traditional black populations, leading to lifestyle changes ...

Motivation - Alcohol consumption is one of the major risk factors of cardiovascular disease (CVD). Excessive alcohol drinking is the fifth leading cause of death worldwide and the prevalence of alcohol abuse continues to ...

Motivation - In South Africa, various transitional changes parallel detrimental modifications in lifestyle behaviour of especially the lower socio-economic communities. We are currently double-burdened by a high prevalence ...

Motivation: The prevalence of cardiovascular dysfunction, especially hypertension, in Africans has increased dramatically over the past few decades. Despite considerable in- depth studies, cardiovascular diseases remain ...

BACKGROUND Cardiovascular disease (CVD) is a major health problem worldwide. In South Africa, the prevalence of cardiovascular disease (CVD) is often underestimated. The prevalence of CVD is very high, especially in urban ...

Motivation - A close association exists between hypertension and arterial stiffness. Whether the increased arterial stiffness seen in hypertensives are due to structural or functional adaptations in the vasculature is ...

Motivation - The human immunodeficiency virus (HIV) continues to be a global health concern, with an estimation of 38 million people living with HIV. Out of these 38 million people living with HIV, 70% are residing in ...

Background and motivation - Plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor known for its classic role in fibrinolysis, has in recent years gained attention for its association with impaired vascular ...