Now showing items 1-3 of 3
The effect of Pheroid® technology on the bioavailability of artemisone in primates
Malaria is one the world’s most devastating diseases. Several classes of drugs are used to treat malaria. Artemisinin combination therapy is the first line treatment of uncomplicated malaria. The artemisinin derivative, ...
The effect of Pheroid™ technology on the bioavailability of quinoline–based anti–malarial compounds in primates
(North-West University, 2012)
Resistance against anti-malarial drugs remains one of the greatest obstacles to the effective control of malaria. The current first-line treatment regimen for uncomplicated P.falciparum malaria is based on artemisinin ...
Radio-labelling as a tool to investigate the absorption and bio-distribution of selected antimalarial drugs
Previous studies have shown that the formulation of an active pharmaceutical ingredient (API) entrapped in the Pheroid® (Pheroid for simplification) delivery system enhances absorption of the API, suppresses its metabolism, ...