Search
Now showing items 1-10 of 340
Topical delivery of selected female hormones from different formulations
(North-West University (South-Africa), 2020)
Skin ageing is an unavoidable biological phenomenon inextricably linked to menopause. The rapid and drastic decline in oestrogen levels brought about by menopause has a profound effect on skin integrity and physiology, ...
The use of grapeseed oil emulsions for the transdermal delivery of selected statins
(North-West University (South-Africa), 2020)
Statins are used for the medical treatment of hypercholesterolemia, but after oral administration, it may cause gastro-intestinal disturbances and first-pass hepatic metabolism may decrease the bioavailability. Hence, the ...
Development of a topical self-emulsifying drug delivery system for optimised delivery
(North-West University (South-Africa), 2020)
In order to achieve successful receptor binding affinity at complex pharmacological targets the majority of drugs are of a lipophilic nature. However, optimisation of drug delivery systems for lipophilic drugs presents ...
Epidemiology of childhood cancer in a section of the private health sector of South Africa
(North-West University (South-Africa), 2020)
The study aimed at determining the incidence, prevalence and trends of childhood cancers over time, as well as identifying the common coexisting conditions in children and adolescents on treatment for cancer in the private ...
Transdermal delivery of selected statins formulated in grapeseed oil emulsions
(North-West University (South-Africa), 2020)
Hypercholesterolemia can be described as high levels of low-density lipoproteins (LDL) that accumulate in the cells of the body including the liver, spleen and the intestines. Cholesterol is eliminated by increasing ...
Pharmacists’ perception towards pharmacovigilance and the reporting of adverse drug reactions in South Africa.
(North-West University (South-Africa), 2020)
Pharmacovigilance in South Africa is not being utilised in a desired manner. This study highlights pharmacists’ expectations and limitations towards adverse drug reaction reporting in their pharmaceutical sector. Current ...
In vitro investigation of wound dynamics using Absorbatox® containing organic acid(s)
(North-West University (South-Africa), 2020)
The skin provides an essential protective barrier between the internal tissues and the environment. A wound is defined as a defect or a break in the skin barrier as a result of physical or thermal damage. Wounds may also ...
Evaluation of nitrocatechol bearing cyclic chalcones and related analogues as dual monoamine oxidase and catechol-O-methyltransferase inhibitors
(North-West University (South-Africa), 2020)
Parkinson’s disease (PD) is one of the leading causes of disability in the world. A better understanding of the aetiology of this disorder will lead to better medications, and would improve the quality of life for millions ...
Influence of blood culture results on antimicrobial prescribing in a private hospital in North West, South Africa
(North-West University (South-Africa), 2020)
Blood culture laboratory testing and the results thereof can be seen as a cornerstone for optimised antimicrobial treatment and has the power to influence and change how effectively patients are treated with antibiotics, ...
Personality traits and gender as predictors of risk-taking behaviour among first-year students at the North-West University
(North-West University (South-Africa), 2021)
The aim of the study was to examine personality traits and gender as predictors of risk-taking behaviour among university students. A sample of 312 first-year students studying at the North-West University, Mafikeng Campus, ...