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Now showing items 11-20 of 36
Exploring a marker of cardiac fibrosis and its association with soluble uPAR in a bi–ethnic South African population : the SAfrEIC study
(2013)
Background: Fibulin-1, an extracellular matrix component and mediator in cardiac fibrosis, is expressed in cardiac valves, heart muscles and blood vessels and may contribute to different cardiovascular pathological ...
Haemostatic markers and cardiovascular function in black and white South Africans : the SABPA study
(2015)
Motivation - In the black population of South Africa, cardiovascular disease (CVD) is rapidly increasing due to urbanisation. Stroke is usually accompanied by a pro-thrombotic haemostatic profile. Changing lifestyle factors ...
The relationship between cardiovascular risk factors and knowledge of cardiovascular disease in African men in the North-West Province
(2014)
BACKGROUND Cardiovascular disease (CVD) is a major health problem worldwide. In South Africa, the prevalence of cardiovascular disease (CVD) is often underestimated. The prevalence of CVD is very high, especially in urban ...
Vascular and metabolic profile of 5-year sustained hypertensive versus normotensive black South Africans
(2014)
Motivation - A close association exists between hypertension and arterial stiffness. Whether the increased arterial stiffness seen in hypertensives are due to structural or functional adaptations in the vasculature is ...
Comparing markers of the nitric oxide cycle and their association with ambulatory blood pressure and end organ damage in a bi–ethnic population : a SABPA–study
(North-West University, 2012)
Aims There is a high prevalence of hypertension in the African population and it is known that vascular dysfunction (including nitric oxide (NO) bio-availability markers) play an important role in the development of ...
Oxidative stress and angiogenesis in Africans and Caucasians: the SAfrEIC study
(North-West University, 2012)
Motivation and aim - The prevalence of hypertension is higher in Africans compared to Caucasians. African Americans also show higher levels of oxidative stress. However, literature regarding levels of oxidative stress and ...
The influence of HIV infection on vascular function in an African population
(North-West University, 2010)
The prevention and treatment of non-communicable diseases, such as cardiovascular disease, is marginalized in South Africa by the overwhelming prevalence of human immunodeficiency virus (HIV). HIV infection and/or the ...
Left ventricular structure and urinary metabolomics in young adults: the African- PREDICT study
(North-West University (South-Africa), 2019)
Motivation - African populations are more prone to the development of left ventricular structure abnormalities and dysfunction, however limited information exists on potential metabolic pathways contributing to early left ...
Morning blood pressure surge and its association with arterial function and subclinical target organ damage in young South Africans : the African-PREDICT study
(North-West University (South-Africa), 2019)
Motivation - The accurate measurement of blood pressure remains the most essential technique for the diagnosis and management of hypertension. In addition, there is increasing evidence that the measurement of clinic blood ...
The association of von Willebrand factor and its cleaving protease (ADAMTS13) with health behaviours in young black and white adults: the African-PREDICT study
(North-West University (South-Africa), 2020)
Motivation: Stroke is the second leading cause of death worldwide. In South Africa, the stroke incidence and mortality rate increased significantly in the last 30 years. Elevated plasma levels of the multimeric glycoprotein, ...