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The physico-chemical properties and recrystallisation kinetics of selected amorphous active ingredients
(North-West University (South Africa) , Potchefstroom Campus, 2015)
During the last two to three decades the application of amorphous solid-state forms within the pharmaceutical industry gained much interest. The rationale for this heightened interest is the increased aqueous solubility, ...
Influence of particle size on solubility of active pharmaceutical ingredients
(North-West University, 2012)
The aqueous solubility of an active pharmaceutical ingredient (API) is an important property that requires evaluation during early development and prior to formulation of the final product. With general, experimental, ...
Roxithromycin : a solubility and stability study
(North-West University, 2011)
Roxithromycin is a semi-synthetic, macrolide antibiotic, derived from erythromycin A. It acts as a bacteriostatic drug at low concentrations and a bactericidal drug at high concentrations. It binds to the 50S subunit of ...