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Monocyte chemoattractant protein-1 and large artery structure and function in young individuals : the African-PREDICT study
(North-West University (South Africa) , Potchefstroom Campus, 2015)
Motivation - In sub-Saharan Africa, the burden of cardiovascular diseases (CVD) is increasing at an alarming rate. This may be due to the rapid urbanisation of traditional black populations, leading to lifestyle changes ...
Alcohol intake and cardiovascular function of black South Africans : a 5-year prospective study
(2015)
Motivation - Alcohol consumption is one of the major risk factors of cardiovascular disease (CVD). Excessive alcohol drinking is the fifth leading cause of death worldwide and the prevalence of alcohol abuse
continues to ...
Soluble Urokinase Plasminogen Activator Receptor : exploring its potential as a marker of cardiovascular disease development in black South Africans of the PURE study
(2015)
Motivation - In South Africa, various transitional changes parallel detrimental modifications in lifestyle behaviour of especially the lower socio-economic communities. We are currently double-burdened by a high prevalence ...
Cardiovascular dysfunction in black South Africans: an investigation from various perspectives
(North-West University, 2010)
Motivation: The prevalence of cardiovascular dysfunction, especially hypertension, in Africans has increased dramatically over the past few decades. Despite considerable in- depth studies, cardiovascular diseases remain ...
Usage patterns and cost analysis of angiotensin-converting enzyme (ACE) inhibitors using a medical aid claims database
(North-West University, 2004)
ACE inhibitors have been widely used in the treatment of certain diseases of the
cardiovascular system, the major use being hypertension, since all ACE inhibitors are prescribed for its treatment. ACE inhibitors is also ...
The association of the change in renin with cardiovascular and inflammatory markers in a bi-ethnic population : the SABPA study
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Motivation :
A study done in South Africa stated that black participants have lower renin levels in comparison to white participants, which may be linked to the increased prevalence of cardiovascular disease (CVD) in ...
Prescribing patterns of non-steroidal anti-inflammatory drugs in patients with chronic kidney disease
(North-West University (South Africa) , Potchefstroom Campus, 2015)
The main aim of this study was to characterise the prescribing patterns of non-steroidal anti-inflammatory drugs (NSAIDs) in chronic kidney disease (CKD) patients in the private health sector of South Africa. This was done ...
The cardiovascular profile of the low renin phenotype in a black South African population
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Motivation
Blood pressure is decreasing globally, however, the prevalence of hypertension continues to
increase in Sub-Saharan African countries such as South Africa. Populations of African ancestry
are more likely to ...
The relationship between cardiovascular risk factors and knowledge of cardiovascular disease in African men in the North-West Province
(2014)
BACKGROUND Cardiovascular disease (CVD) is a major health problem worldwide. In South Africa, the prevalence of cardiovascular disease (CVD) is often underestimated. The prevalence of CVD is very high, especially in urban ...
Vascular and metabolic profile of 5-year sustained hypertensive versus normotensive black South Africans
(2014)
Motivation - A close association exists between hypertension and arterial stiffness. Whether the increased arterial stiffness seen in hypertensives are due to structural or functional adaptations in the vasculature is ...