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Cardiovascular disease and reduced pulmonary function in black South Africans : investigating the interplay with markers of systemic inflammation
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Motivation - In South Africa, the process of rapid urbanisation has led to a high prevalence of noncommunicable diseases such as chronic respiratory and cardiovascular diseases which are
accompanied by a high cardiovascular ...
Monocyte chemoattractant protein-1 and large artery structure and function in young individuals : the African-PREDICT study
(North-West University (South Africa) , Potchefstroom Campus, 2015)
Motivation - In sub-Saharan Africa, the burden of cardiovascular diseases (CVD) is increasing at an alarming rate. This may be due to the rapid urbanisation of traditional black populations, leading to lifestyle changes ...
Soluble Urokinase Plasminogen Activator Receptor : exploring its potential as a marker of cardiovascular disease development in black South Africans of the PURE study
(2015)
Motivation - In South Africa, various transitional changes parallel detrimental modifications in lifestyle behaviour of especially the lower socio-economic communities. We are currently double-burdened by a high prevalence ...
The role of endothelin-1 in cardiometabolic and vascular function in a bi-ethnic population : the SABPA study
(North-West University (South Africa) , Potchefstroom Campus, 2017)
Motivation
The black population in South Africa has a high prevalence of hypertension and atherosclerosis. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, has been implicated as an important biomarker in the ...
Genotypic exploration of the fibrinogen phenotype in a black South African population
(North-West University (South Africa) , Potchefstroom Campus, 2016)
INTRODUCTION AND AIM
Increased total and ‘ fibrinogen concentrations are associated with cardiovascular disease
(CVD) risk in part through their effects on fibrin clot properties. Interleukin-6 (IL-6) promotes the
expression ...
The association of the change in renin with cardiovascular and inflammatory markers in a bi-ethnic population : the SABPA study
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Motivation :
A study done in South Africa stated that black participants have lower renin levels in comparison to white participants, which may be linked to the increased prevalence of cardiovascular disease (CVD) in ...
Exploring a marker of cardiac fibrosis and its association with soluble uPAR in a bi–ethnic South African population : the SAfrEIC study
(2013)
Background: Fibulin-1, an extracellular matrix component and mediator in cardiac fibrosis, is expressed in cardiac valves, heart muscles and blood vessels and may contribute to different cardiovascular pathological ...
A critical analysis of iron status indicators in three independent studies of South African primary school children
(2014)
Background The potential dire consequences of iron deficiency (ID) and iron deficiency anaemia (IDA) on childhood development are of major public health concern. Many factors contribute to anaemia, ID being only one ...
Body composition, physical activity and C-reactive protein in children : the PLAY study
(North-West University, 2006)
Obesity is currently the most common and costly nutritional problem in developed countries and ten percent of the world's school-aged children are estimated to be overweight to some extent. Low-grade systemic inflammation ...
The influence of HIV infection on vascular function in an African population
(North-West University, 2010)
The prevention and treatment of non-communicable diseases, such as cardiovascular disease, is marginalized in South Africa by the overwhelming prevalence of human immunodeficiency virus (HIV). HIV infection and/or the ...