Browsing Natural and Agricultural Sciences by Subject "Adaptive response"
Now showing items 1-2 of 2
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Evaluating the involvement of metallothionein l in complex l deficiency : an in vitro study
(North-West University, 2018)Among the inborn errors of energy metabolism, complex I (CI) deficiency is the most frequently encountered and debilitating disorder of the oxidative phosphorylation system. Hallmarks include an early onset, progressive ... -
Investigating the adaptive mitochondrial shuttles and metabolic reprogramming of transporters in complex I (Ndufs4) knockout mice
(North-West University (South Africa), 2022)Mitochondrial disease is one of the most prevalent inherited paediatric disorders among children, with a prevalence of 1 in 5000 children. Leigh syndrome is the result of a Complex I (CI) deficiency and disrupts the redox ...