Browsing Natural and Agricultural Sciences by Subject "Metallothionein"
Now showing items 1-4 of 4
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Establishing the comet assay to determine the effects of different perturbations on DNA repair capacity
(North-West University, 2011)Single cell gel electrophoresis (SCGE), more commonly known as the Comet assay, is an uncomplicated, affordable and versatile method for investigating DNA damage and repair. Existing comet–assay based methods were modified ... -
Evaluation of metallothionein involvement in the modulation of mitochondrial respiration in mice
(North-West University, 2011)Metallothioneins (MTs) are small, non-enzymatic proteins that are involved in cellular detoxification and metal homeostasis because of their high cysteine content. MTs have also been identified as one of the vast number ... -
Fish health, condition and biomarkers : a mechanistic and environmental perspective on copper pollution
(North-West University, 2005)Suid-Afrika het beperkte waterhulpbronne, wat tot gevolg het dat die beskikbare water van baie hoe kwaliteit moet wees. Ongelukkig word die kwaliteit van ons hulpbronne deur antropologiese impakte bedreig. Tot baie onlangs ... -
Investigation into the protection of mitochondrial disease pathology by metallothionein overexpression
(North-West University (South Africa), 2020)Mitochondrial diseases (MD), such as Leigh Syndrome (LS), present with severe neurological and muscular phenotypes in patients, but have no known cure and limited treatment options. Based on their neuroprotective effects ...