Browsing Natural and Agricultural Sciences by Subject "DNA methylation"
Now showing items 1-3 of 3
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An analysis of the effect of transformation on global– and gene–specific DNA methylation in four cultured cell lines
(North-West University, 2010)DNA methylation plays a role in several biological functions, such as gene expression regulation, and several endogenous and exogenous factors affect these DNA methylation patterns in the cell. One such alteration of a ... -
A study of the early DNA methylation events in oxidative stressed cultured mammalian cells
(North-West University, 2012)Cells are continuously exposed to reactive oxygen species (ROS) causing oxidative stress. Cells can withstand and counteract ROS using defence mechanisms which range from free radical scavengers, antioxidant enzymes and ... -
Tyrosinemia type I as a model for studying epigenetic events in the aetiology of metabolic disease associated hepatocarcinoma
(North-West University, 2011)Occupational risk management can be a catalyst in generating superior returns for all stakeholders on a sustainable basis. A number of companies in South Africa have implemented Cardinal Rules of Safety adopted from ...