Browsing Natural and Agricultural Sciences by Subject "Reverse genetics"
Now showing items 1-3 of 3
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Investigating the role of rotavirus GS10(NSP4) and GS6(VP6) in reassortment
(North-West University (South Africa), 2023)Rotaviruses are dsRNA viruses and are the leading causative agent of severe gastroenteritis. All current licenced rotavirus vaccines contain live-attenuated strains and are capable of reassorting their genome segments ... -
Preparatory investigations for developing a transcript–based rotavirus reverse genetics system
(North-West University, 2012)Reverse genetics systems that are based on either viral transcripts or cDNA genome segments cloned in plasmids have recently been reported for some of the dsRNA viruses of the Reoviridae family, namely African horsesickness ... -
Recovery of an African horsesickness virus VP2 chimera using reverse genetics
(North-West University (South Africa), Potchefstroom Campus, 2016)African horsesickness (AHS) is a devastating disease which causes mortality in more than 95% of fully susceptible horses. There are nine serotypes of the etiological agent, African horsesickness virus (AHSV) exhibiting ...