Browsing Natural and Agricultural Sciences by Subject "Urine"
Now showing items 1-4 of 4
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Carnitine conjugation profiling in a selected cohort of patients with chronic fatigue syndrome
(North-West University, 2019)Chronic fatigue syndrome (CFS) is classified by the World Health Organisation (WHO) as a non-communicable disease. Fatigue is a symptom commonly experienced by many individuals and is also a symptom associated with a wide ... -
Investigating tissue-specificity in a mouse model of Leigh Syndrome using metabolomics
(North-West University (South Africa), 2022)Mitochondrial disease (MD) is one of the most challenging groups of inborn disorders featuring a tissue-specific vulnerability, governed by largely unknown mechanisms. The value of metabolomics in multi-systemic MD ... -
A metabolomics investigation of tuberculous meningitis in infants and children
(North-West University (South Africa), 2016)This thesis, titled: ‘A metabolomics investigation of Tuberculous Meningitis in infants and children’, deals with tuberculous meningitis (TBM), the most severe complication of tuberculosis (TB) and major pandemic of our ... -
Urinary metabolomics investigation of Ndufs4 knockout mice
(North-West University (South Africa), 2020)Mitochondrial diseases (MDs) are the most common inborn errors of metabolism, with an estimated prevalence of approximately 1 in 5 000 live births, and are mainly caused by deficiencies of complex I (CI) of the oxidative ...