Browsing Natural and Agricultural Sciences by Subject "reverse genetics"
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Generation of a set of SA11 expression plasmids for the development of a T7-RNA polymerase-dependent rotavirus reverse genetic system
(North-West University, 2018)Rotavirus (RV) is a member of the family Reoviridae which contains a segmented double-stranded RNA genome comprised of 11 double-stranded RNA genome segments. Rotavirus is still the leading cause of severe diarrhoea worldwide ... -
Preparation of a set of rotavirus SA 11 transcription plasmids for T7- transcript based reverse genetics
(North-West University, 2018)Rotaviruses belong to the Reoviridae family, and rotavirus infection is the biggest contributor to diarrhoea-related death in the world for children under the age of five years. The rotavirus genome consists of 11 ...