Show simple item record

dc.contributor.authorAntwis, Rachel Ellen
dc.contributor.authorWeldon, Ché
dc.date.accessioned2018-03-06T13:57:33Z
dc.date.available2018-03-06T13:57:33Z
dc.date.issued2017
dc.identifier.citationAntwis, R.E. & Weldon, C. 2017. Amphibian skin defences show variation in ability to inhibit growth of Batrachochytrium dendrobatidis isolates from the Global Panzootic Lineage. Microbiology, 163:1835-1838. [https://doi.org/10.1099/mic.0.000570]en_US
dc.identifier.issn1350-0872
dc.identifier.issn1465-2080 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/26532
dc.identifier.urihttps://doi.org/10.1099/mic.0.000570
dc.identifier.urihttp://mic.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000570
dc.description.abstractThe fungal pathogen Batrachochytrium dendrobatidis has caused declines and extinctions in hundreds of amphibian species across the world. Virulence varies among and within lineages; the Global Panzootic Lineage (GPL) is the most pathogenic, although there is also variation in lethality among GPL isolates. Amphibians have a number of defences against pathogens, and skin products including the microbiota and host peptides have considerable influence over disease progression. Here we demonstrate that the collective skin products (the mucosome) of two amphibian species show significant variation in their ability to inhibit different globally distributed isolates of GPL. This may in part explain the variation in disease susceptibility of hosts to different strains of B. dendrobatidis. More work is required to identify particular traits associated with mucosomes that confer broad-spectrum inhibition across GPL in order to facilitate the development of prophylaxis and/or treatments for chytridiomycosis in situen_US
dc.language.isoenen_US
dc.publisherMicrobiology Societyen_US
dc.subjectInnate defencesen_US
dc.subjectPathogen susceptibilityen_US
dc.subjectChytridiomycosisen_US
dc.subjectMicrobial symbiontsen_US
dc.subjectMucosomeen_US
dc.subjectSkin productsen_US
dc.subjectFungal pathogensen_US
dc.titleAmphibian skin defences show variation in ability to inhibit growth of Batrachochytrium dendrobatidis isolates from the Global Panzootic Lineageen_US
dc.typeArticleen_US
dc.contributor.researchID12384488 - Weldon, Ché
dc.contributor.researchID26759470 - Antwis, Rachael Ellen


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record