Gold nanostar colorimetric detection of fructosyl valine as a potential future point of care biosensor candidate for glycated haemoglobin detection
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Date
2019Author
Mulder, Danielle Wingrove
Phiri, Masauso Moses
Vorster, Barend Christiaan
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Show full item recordAbstract
Diabetes Mellitus is a growing global concern. The current methods used to detect glycated
haemoglobin are precise, however, utilise expensive equipment, reagents and consumables. These
are luxuries which rural communities cannot access. The nanotechnology methods which have been
developed for glycated haemoglobin detection are predominantly electrochemically based, have
complicated lengthy fabrication processes and utilise toxic chemicals. Here a fructosyl amino acid
oxidase gold nanostar biosensor has been developed as a potential future point of care biosensor
candidate for glycated haemoglobin detection. The workup done on this biosensor showed that it
was able to give a spectrophotometric readout and colorimetric result with naked eye detection in
blank serum spiked with fructosyl valine
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http://hdl.handle.net/10394/33355https://www.mdpi.com/2079-6374/9/3/100/pdf
https://doi.org/10.3390/bios9030100