Pathological consequences of drug abuse: implication of redox imbalance. Editorial
View/ Open
Date
2019Author
Schiavone, Stefania
Harvey, Brian H.
Neri, Margherita
Metadata
Show full item recordAbstract
The onset, progression, and outcome of numerous pathological conditions, affecting different organs and systems, have
been widely reported to be significantly impacted by the
abuse of psychoactive compounds. In the last decades, preclinical and clinical reports have contributed to a lively scientific debate on the possible pathogenic role that redox
imbalance, defined as a disequilibrium between reactive
oxygen species (ROS) generating and degrading systems,
plays in this scenario [1]. Moreover, increasing interest has
focused on the possibility that enhanced ROS production or
decreased antioxidant defenses in different body compartments, such as the blood, central nervous system (CNS), cardiovascular, gastrointestinal, and respiratory apparatuses
may represent reliable biomarkers that will enable the detection of both the early phases of drug abuse-associated complications and the response to pharmacological treatments
URI
http://hdl.handle.net/10394/33506http://downloads.hindawi.com/journals/omcl/2019/4780852.pdf
https://doi.org/10.1155/2019/4780852
Collections
- Faculty of Health Sciences [2386]